Bayesian Peak Picking for NMR Spectra
نویسندگان
چکیده
منابع مشابه
Bayesian Peak Picking for NMR Spectra
Protein structure determination is a very important topic in structural genomics, which helps people to understand varieties of biological functions such as protein-protein interactions, protein-DNA interactions and so on. Nowadays, nuclear magnetic resonance (NMR) has often been used to determine the three-dimensional structures of protein in vivo. This study aims to automate the peak picking ...
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MOTIVATION Picking peaks from experimental NMR spectra is a key unsolved problem for automated NMR protein structure determination. Such a process is a prerequisite for resonance assignment, nuclear overhauser enhancement (NOE) distance restraint assignment, and structure calculation tasks. Manual or semi-automatic peak picking, which is currently the prominent way used in NMR labs, is tedious,...
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ژورنال
عنوان ژورنال: Genomics, Proteomics & Bioinformatics
سال: 2014
ISSN: 1672-0229
DOI: 10.1016/j.gpb.2013.07.003